Super K with Advanced K2 Complex provides the three forms of vitamin K that can be utilized by the body: vitamin K1 and dual forms of K2, MK-4 and MK-7. This comprehensive vitamin K formula promotes both bone and arterial health. So boost your vitamin K levels with the one-two punch of both K1 and K2, add Super K with Advanced K2 Complex to your nutrient regimen today!

Benefits at a Glance:

• Maintains bone density by facilitating calcium transport into bone
• Promotes a healthy heart and vascular system
• Includes the most bioavailable forms of vitamin K1 and K2
• Bioavailable over a sustained 24-hour period

The method by which vitamin K supports bones and arteries is related to its relationship with calcium. Research has shown that low vitamin K status interferes with the function of a protein called matrix Gla-protein (MGP). This protein is vitamin K dependent and must be carboxylated to function properly.

Without adequate vitamin K, MGP remains uncarboxylated. Studies have found that uncarboxylated MGP accumulates at the site of arterial calcification. Without normal levels of carboxylated MGP, calcium in the blood can bind to the arterial wall resulting in calcification.

Health benefits of vitamin K

The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that tracked 4,800 subjects for seven years, revealed that people who consume the most dietary K2 have healthier hearts when compared to people who consume the least. Additional studies have shown that higher vitamin K levels also correspond to less calcium deposits in the aorta, and can even cause a 37% regression of preformed arterial calcification.

Different forms of Vitamin K

Unfortunately, obtaining enough vitamin K through the diet can be difficult. The most common form of vitamin K, known as K1, is present in leafy green vegetables. Not only do many people avoid these vegetables, the K1 is tightly bound to plant fibers and not easily absorbable.

In contrast, vitamin K2, which is found in meat, egg yolks, and dairy, is up to 10 times more bioavailable than K1 and remains active in the body for far longer. If you're avoiding these foods for health reasons, it’s essential to take a K2 supplement.

Super K with Advanced K2 Complex makes it easier to get enough vitamin K by including two forms of vitamin K2, MK-4 and MK-7. The MK-4 form is the most rapidly absorbed type of vitamin K. However, it only lasts in the bloodstream for a few hours. In contrast, the MK-7 form is available to the body for a full 24-hour period at much higher levels.

A complete Vitamin K supplement

Combining two forms of vitamin K2 provides both rapid and sustained absorption of this critical nutrient, so your healthy blood levels are maintained throughout the day. Just one daily softgel of Super K with Advanced K2 Complex provides 100 mcg of vitamin K2 (MK-7); 1,000 mcg of vitamin K2 (MK-4); and 1,500 mcg of vitamin K1. This K2 complex, plus a strong dose of K1, makes this comprehensive formula an excellent way to get your vitamin K!

D-ribose, a carbohydrate molecule found in every living organism, facilitates the production of ATP.2

In studies of healthy athletes, supplying fatigued muscle cells with D-ribose quickly restored ATP levels to normal.3-6 By helping to rapidly refill depleted energy stores, D-ribose may be especially beneficial for heart health.

D-Ribose Tablets and D-Ribose Powder can help speed energy recovery, increase energy reserves and maintain healthy energy levels in heart and muscle tissue.

Studies show that selenium, a trace mineral, is an important common denominator among some of the world’s longest-living people. Selenium promotes heart health, brain health, and supports longevity. And our Super Selenium Complex formula provides three unique forms of selenium along with vitamin E for optimal health and longevity support.

Benefits at a Glance

• Combines three unique forms of selenium plus vitamin E
• Supports your body against oxidative damage
• Supports normal thyroid and immune function in healthy individuals
• Promotes heart health, brain health, and healthy cell division

Three forms of selenium + vitamin E

Selenium is available in several different forms. Each form of selenium acts along a different pathway to support healthy cell division. For optimized selenium support, one should supplement with all three forms of selenium.

Super Selenium Complex delivers sodium selenite, L-selenomethionine, and selenium-methyl L-selenocysteine. Super Selenium Complex also contains a small amount of vitamin E because it has been shown to work synergistically with selenium.1

Antioxidant, thyroid, and immune support

Selenium is also an important factor when it comes to its ability to fight one of the primary causes of premature aging: oxidative damage. That’s because the body utilizes selenium to make glutathione peroxidase, an endogenous antioxidant enzyme. Selenium also supports normal thyroid and immune function in healthy individuals.

Cardiovascular health, brain health, and healthy cell division

Selenium plays a role in healthy cell division. But its ability to promote a healthy inflammatory response and quench free radicals has led scientists to explore its beneficial effects in regards to other conditions involving oxidative damage — particularly for heart and brain health.

Selenium is a vital nutrient for healthy cell division. It also protects against oxidative stress, promotes heart and brain health, and may be key to promoting longevity — all reasons to add Super Selenium Complex to your nutritional regimen today.

A longstanding problem is that zinc absorption can be limited1 and certain molecules in plant sources and grains can further inhibit absorption.

Life Extension has developed a low-cost formulation combining the well-established, enhanced bioavailability of OptiZinc with zinc citrate to provide a potent 50 milligram dose of zinc in a single capsule.

Beyond immune support, zinc plays other crucial roles. It is an essential component of superoxide dismutase, one of your body's most powerful natural antioxidants. Zinc stimulates the activity of about 300 enzymes that promote biochemical reactions in your body. This key mineral is also an integral component of vital hormones and supports protein and DNA synthesis, insulin production, as well as thyroid and bone metabolism. Zinc supports cardiovascular and neurological health, and helps maintain vision in the elderly.

Age-related immune decline is partly due to the decreasing size and function of the thymus gland. Evidence suggests that zinc may help maintain healthy function of the thymus gland in elderly people.

OptiZinc is a superior bioavailable form of zinc. It is assimilated more easily than ordinary zinc because it is comprised of one of the most absorbable forms of zinc — zinc methionate (methionine). Published studies show that it results in higher blood levels compared to other forms of zinc.

In Europe and Asia, herbal liver tonics have been in common use for centuries. The effectiveness of the herbs used has been validated during the past decades through modern research and clinical studies. These herbs generally contain antioxidants, cell membrane-stabilizing agents, bile secretion-enhancing compounds, or nutrients that inhibit the depletion of endogenous antioxidants such as glutathione. Hepatoprotection is beneficial not only for the liver but also for the overall health and vitality of the body.

Milk thistle extract has long been valued for its role in ensuring healthy liver function, and it is also a powerful antioxidant.1-6 Milk thistle extract consists of silibinins and other similar compounds. Until recently, scientists focused their research on silibinins, as they were the most abundant and biologically active ingredient found in milk thistle extract.7,8 Highly advanced extraction technology has now enabled scientists to isolate other silymarin constituents and test their efficacy against various cell

European Milk Thistle contains standardized, top-grade potencies of silymarin, silibinins, isosilybin A and isosilybin B, providing the full spectrum of milk thistle’s liver- and prostate-supportive compounds.

The botanical extract in European Milk Thistle is a triple standardized milk thistle extract. In addition to an optimal 80% standardization of the main active compounds, silymarin flavonolignans, this formula is further standardized to three highly active isomers — silibinins and isosilybin A and B.

The primary source of energy for all cellular processes is a molecule known as ATP (adenosine triphosphate). Healthy, active cells constantly replenish their supply of ATP to produce vital cellular energy.1However, under conditions of stress, injury, or aging, critical body tissues such as heart and skeletal muscles cannot produce ATP quickly enough to perform optimally.

D-ribose, a carbohydrate molecule found in every living organism, facilitates the production of ATP.2

In studies of healthy athletes, supplying fatigued muscle cells with D-ribose quickly restored ATP levels to normal.3-6 By helping to rapidly refill depleted energy stores, D-ribose may be especially beneficial for heart health.

D-Ribose Tablets and D-Ribose Powder can help speed energy recovery, increase energy reserves and maintain healthy energy levels in heart and muscle tissue.

An age-related effect is the reduction in the energy-producing components of the cell, resulting in reduced cellular metabolic activity, and the accumulation of cellular debris. L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fatty acids from the cytosol into the mitochondria within the cell, where fats are oxidized to produce the cellular energy (adenosine triphosphate or ATP).

Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-L-carnitine is an endogenous mitochondrial membrane compound that helps maintain mitochondrial bioenergetics and lowers the increased oxidative stress associated with aging. Acetyl-L-carnitine and L-carnitine are absorbed into the bloodstream efficiently. Both are effective at carrying long-chain fatty acids across the membrane into the mitochondria where they are burned for energy production and utilized efficiently by the cells. Acetyl-L-carnitine also crosses the blood-brain barrier and guards against oxidative damage. Amyloid-beta peptide is a principal component of plaques and is thought to be a contributor to the aging process. Acetyl-L-carnitine exerts protective effects against such neurotoxicity and oxidative stress.

Acetyl-L-carnitine (ALC) easily crosses the blood-brain barrier and may have potential in exerting unique neuroprotective, neuromodulatory and neurotrophic properties. ALC may support youthful memory function, improve mitochondrial structure and function, inhibit age-related oxidative damage, and restore the activity of key enzymes.

Published studies have shown the critical importance of lipoic acid in preserving youthful cellular energy by supporting healthy mitochondrial function. Unlike other forms of lipoic acid, Super R-Lipoic Acid is more bioavailable, stable, and potent, achieving 10–30 times higher peak blood levels than pure R-lipoic acid. This unique sodium-R-lipoate can help you reach peak plasma concentrations within just 10–20 minutes of supplementation. Super R-Lipoic Acid provides more of the active "R" form of lipoic acid than any other supplement. Try this next-generation lipoic acid today!

DHEA is the body's most abundant circulating hormone. But as we age, DHEA levels begin to decline. Supplementing with DHEA can help support healthy hormone levels, promote healthy immune function,1 circulatory health, healthy mood, lean muscle mass, sexual function,2 and more.

Benefits at a Glance

• Maintains youthful DHEA hormone balance
• Encourages healthy immune function1 and cardiovascular health3
• Helps support and maintain lean muscle mass4
• Promotes healthy mood, sexual function,2 well-being,5 and more

More facts about DHEA

Levels of DHEA in the blood are high in early adulthood, decreasing progressively thereafter.6 Studies indicate that maintaining optimal DHEA levels offers a variety of health benefits, including, positive effects on mood and quality of life, maintaining lean muscle mass, and more. Increased circulating levels of DHEA may improve overall well-being and sexual function as well.

Body composition, mood, and more

In a randomized, double-blind, placebo-controlled study, 10 months of DHEA supplementation in elderly individuals resulted in increased strength and lean muscle mass from resistance exercise.4 DHEA regimens offer beneficial effects such as promoting optimal sexual health,7,8 improving memory collection and mood, and may also have beneficial effects on the brain.9

Cardio, circulatory, and bone health

DHEA has beneficial cardiovascular effects.3 It also promotes healthy bones.10-12 In a randomized, double-blind, controlled trial, one year of DHEA supplementation helped increase bone mineral density in the hips of older adults and spinal bone mineral density in older women.1

- Dehydroepiandrosterone
- Promotes Optimal Hormone Levels
- Dietary Supplement
- Non-GMO

A healthy thyroid gland not only acts as the body’s thermostat, but it's also one of the major regulators of metabolism, including fat burning for energy.

Life Extension introduces Triple Action Thyroid, a formulation that combines critical nutrients that have been scientifically demonstrated to support healthy thyroid function.

Optimal thyroid function can help improve energy levels, motivation, metabolism, healthy weight management, and concentration.

The new Triple Action Thyroid formula provides:

• Ashwagandha, an adaptogenic herb, shown to support natural production of the thyroid hormone T4. In one study, researchers found that 500 mg per day of standardized ashwagandha extract enhanced T4 levels.
• Guggul, an extract of Commiphora mukul, shown in one study to support the activity of the enzyme that converts T4 into the most active thyroid hormone, T3.
• Korean Ginseng, found in one study to reduce levels of the inactive, thyroid hormone-inhibiting reverse T3 (rT3) and support healthy T3 and T4 levels.

The following additional nutrients are included in Triple Action Thyroid to further enhance benefits:

• Iodine and tyrosine, which are required for thyroid hormone production,
• Vitamin B12, a sufficient level of which is needed for healthy thyroid activity,
• Vitamin A, an important nutrient for supporting healthy serum T3 (active) levels.

The suggested dose of Triple Action Thyroid is one capsule twice daily. If blood testing for thyroid function reveals less than optimal hormone levels, consult your physician for further evaluation.

Mitochondria, the powerhouses found within human cells, produce the energy that vital tissues need to keep us vibrant, healthy, and young.1 Normal levels of carnitine support optimum functioning of mitochondria. The problem is that over time, levels of carnitine decline in all of our tissues,2,3 reducing cellular energy production and metabolic activity.4-10 The answer is carnitine supplementation, because carnitine helps:

• Maintain cellular metabolic activity by assisting in the intracellular transport of fatty acids from the cell fluid into the mitochondria where fats are oxidized to generate cellular energy.11-13
• Inhibit excess accumulation of cellular debris.14-16
• Support a healthy concentration of nitric oxide, which helps endothelial cells relax and maintain blood flow—supporting proper blood pressure.17-19
• Maintain healthy body fat composition, which in turn supports insulin sensitivity and healthy blood sugar levels already within normal range.20,21
• Support brain cells’ natural defenses against age-related memory and cognitive decline.22,23